Hyperthermic Intraperitoneal Chemotherapy (HIPEC)

​Hyperthermic Intraperitoneal Chemotherapy (HIPEC)

Advanced treatment for abdominal cancers

The Christ Hospital Cancer Center is one of few cancer centers in the nation to offer hyperthermic intraperitoneal chemotherapy (HIPEC)—a highly concentrated, heated chemotherapy treatment that is used to combat difficult-to-treat cancers that have spread to the lining of the abdominal cavity from other sources of primary cancer, such as:

  • Appendix Cancer

  • Colon & Rectal Cancer

  • Gastric Cancer & Stomach

  • Ovarian Cancer

  • Peritoneal Mesothelioma

  • Primary Peritoneal Cancer or Primary Abdominal Cancer

  • Pseudomyxoma Peritonei

How does HIPEC work?

HIPEC is a highly concentrated, heated chemotherapy treatment delivered directly to the abdomen during surgery. Unlike systemic chemotherapy delivery, which circulates throughout the body, HIPEC delivers chemotherapy directly to cancer cells in the abdomen. This allows for higher doses of chemotherapy.

Before HIPEC is administered, the surgeon uses cytoreductive surgery to remove all visible tumors that can be seen in the peritoneal cavity. Following this step, the heated chemotherapy is immediately administered directly into the abdominal cavity.  The chemotherapy circulates in the abdominal cavity for up to two hours then is drained and the incision is closed.  The HIPEC procedure is designed to attempt to kill all remaining cancer cells, including any that cannot be seen with the naked eye.   

What are the advantages of HIPEC?

  • HIPEC allows for a higher concentration of chemotherapy to be delivered directly to the affected area instead of the whole body.  Administering chemotherapy this way is more likely to kill any remaining or lingering cancer cells as compared to standard chemotherapy treatment. 

  • It is best at killing cancer cells that are too small to be seen with the naked eye.

  • HIPEC is usually delivered in one treatment where standard chemotherapy requires several sessions.  

  • There are fewer side effects with HIPEC than there are with standard chemotherapy because the chemotherapy is contained within the abdominal cavity. 

HIPEC treatment at The Christ Hospital

Our program is led by Rod Flynn, MD, a surgical oncologist who played an integral role in the development of the HIPEC program at The Cancer Centers of America before making this niche treatment available at The Christ Hospital in Cincinnati. Dr. Flynn is passionate about using HIPEC to improve the quantity and quality of life and giving hope to patients with specific types of advanced cancer who were otherwise resigned to hospice. 

To learn more about HIPEC or for an appointment, contact our nurse navigator by calling 513-585-0694.