CINCINNATI (August 27, 2024) – The Christ Hospital Health Network performed the first procedure in southwest Ohio using the AGENT™ Drug-Coated Balloon (DCB) to treat a patient with coronary artery disease experiencing in-stent restenosis (ISR). The AGENT™ DCB was approved by the U.S. Food and Drug Administration (FDA) in 2024, supported by clinical trial findings and has been used to treat more than 100,000 patients globally.
ISR, the narrowing of a previously stented coronary vessel by plaque or scar tissue, accounts for 10% of all percutaneous coronary interventions in the U.S. The AGENT™ DCB is coated with the anti-restenotic drug paclitaxel, which is delivered to the artery wall via a proprietary technology to help prevent ISR reoccurrence, and without leaving behind another layer of metal stenting.
“We are pleased to have performed our first procedure using the AGENT Drug-Coated Balloon to treat coronary in-stent restenosis in a patient with coronary artery disease,” said John Corl, MD, an interventional cardiologist that performed the first procedure at The Christ Hospital Health Network. “This approach enables us to help prevent reoccurrence of this challenging condition and without leaving behind another layer of permanent metal implants.”
Previously, traditional therapies to treat ISR in the United States have included placing additional layers of metal stents, uncoated balloon angioplasty and radiation, all of which may not provide ideal outcomes in some cases.
If you’d like to view animation of the procedure, click here and to read more about AGENT™ DCB, click here.
About The Christ Hospital Health Network
The Christ Hospital Health Network consists of an acute care hospital located in Mt. Auburn, a remote hospital location in Liberty Township, five ambulatory outpatient centers and dozens of medical offices throughout the region. For more than 130 years, The Christ Hospital has provided compassionate care to those it serves. Made up for more than 1,300 physicians and more than 6,500 team members, our mission is to improve the health of our community by providing exceptional outcomes in an affordable way. The Network was recognized by U.S. News & World Report as the #1 hospital in the Cincinnati Region and named to Newsweek’s World’s Best Hospitals list in 2024. It is also a Press Ganey Guardian of Excellence Award recipient, which recognizes top-performing healthcare organizations that achieve the 95th percentile or above of performance in patient experience.