For more information about cardiovascular clinical research at The Christ Hospital, visit the Lindner Research Center.
Ahmed A, Alsidawi S, Bae R, Cavalcante J, Fukui M, Gossl M, Sorajja P and Garcia S. Changes in quality of life in patients with low-flow aortic stenosis undergoing transcatheter aortic valve replacement. Catheter Cardiovasc Interv. 2020.
Elbadawi A, Elgendy IY, Megaly M, Saad M, Garcia S, Abbott JD, Aronow H, Gafoor S, Jneid H and Sorajja P. Temporal Trends and Outcomes of Transcatheter Mitral Valve Repair Among Nonagenarians. JACC Cardiovasc Interv. 2020.
Anantha-Narayanan M, Malik U, Mbai M, Megaly M, Florea V, Sharma A, Cavalcante JL and Garcia S. Impact of diastolic dysfunction on long-term mortality and quality of life after transcatheter aortic valve replacement. Catheter Cardiovasc Interv. 2020;95:1034-1041.
Daniels MJ, Garcia S. Inspiring Resilience in the Pulmonary Position – Is a Paradigm Shift Due in Congenital Heart Disease? Structural Heart 2020:1-3.
Megaly M, Sorajja, P, Cavalcante J, Pershad A, Gossl M, Abraham B, Omer M, Elbadawi A, Garcia S. Ischemic Stroke With Cerebral Protection System During Transcatheter Aortic Valve ReplacementJ Am Coll Cardiol Intv 2020;13:2149–55.
Bohm M, Kario K, Kandzari DE, Mahfoud F, Weber MA, Schmieder RE, Tsioufis K, Pocock S, Konstantinidis D, Choi JW, East C, Lee DP, Ma A, Ewen S, Cohen DL, Wilensky R, Devireddy CM, Lea J, Schmid A, Weil J, Agdirlioglu T, Reedus D, Jefferson BK, Reyes D, D'Souza R, Sharp ASP, Sharif F, Fahy M, DeBruin V, Cohen SA, Brar S, Townsend RR and Investigators SH-OMP. Efficacy of catheter-based renal denervation in the absence of antihypertensive medications (SPYRAL HTN-OFF MED Pivotal): a multicentre, randomised, sham-controlled trial. Lancet. 2020;395:1444-1451.
Elbadawi A, Elgendy IY, Megaly M, Ugwu J, Shahin HI, Al-Azizi K, Garcia S, Abbott JD, Gafoor S, Kleiman NS and Goel SS. Trends and Outcomes of Transcatheter Aortic Valve Implantation Among Solid Organ Transplant Recipients. Am J Cardiol. 2021;138:122-124.
Hammadah M, Ponce C, Sorajja P, Cavalcante JL, Garcia S and Gossl M. Point-of-care ultrasound: Closing guideline gaps in screening for valvular heart disease. Clin Cardiol. 2020;43:1368-1375.
Megaly M, Han K, Sedhom R, Aboulhosn J, Moga F, Mudy K, Daniels MJ, Elbadawi A, Omer M, Mosleh W, Cavalcante JL and Garcia S. Outcomes of percutaneous and surgical pulmonary valve implantation. Cardiovasc Revasc Med. 2021
Megaly M, Sedhom R, Abdelmaseeh P, ElBebawy B, Goel SS, Karam J, Pershad A, Brilakis ES and Garcia S. Complications of the MANTA closure device. Insights from MAUDE database. Cardiovasc Revasc Med. 2021.
Lopes BBC, Sorajja P, Hashimoto G, Fukui M, Bapat VN, Du Y, Bae R, Schwartz RS, Stanberry LI, Enriquez-Sarano M, Garcia S, Lesser JR and Cavalcante JL. Tricuspid Anatomic Regurgitant Orifice Area by Functional DSCT: A Novel Parameter of Tricuspid Regurgitation Severity. JACC Cardiovasc Imaging. 2021.
Hammadah M, Han BK, de Oliveira Nunes M, Aboulhosn JA, Zahn EM, Babaliaros V, Daniels MJ, Cavalcante JL, Lesser JR and Garcia S. Hypoattenuated Leaflet Thickening After Transcatheter Pulmonary Valve Replacement With the SAPIEN 3 Valve. JACC Cardiovasc Imaging. 2021.
Guddeti RR, Pajjuru VS, Walters RW, Garcia S and Alla VM. Impact of gender on in-hospital mortality and 90-day readmissions in patients undergoing transcatheter edge-to-edge mitral valve repair: Analysis from the National Readmission Database. Catheter Cardiovasc Interv. 2021.
Shroff GR, Bangalore S, Bhave NM, Chang TI, Garcia S, Mathew RO, Rangaswami J, Ternacle J, Thourani VH, Pibarot P, American Heart Association Council on the Kidney in Cardiovascular D and Stroke C. Evaluation and Management of Aortic Stenosis in Chronic Kidney Disease: A Scientific Statement From the American Heart Association. Circulation. 2021;143:e1088-e1114.
Morcos R, Megaly M, Desai A, Alkhouli M, Saad M, Luna M, Garcia S, Khalili H and Maini B. The transseptal puncture experience: Safety insights from FDA MAUDE database. Catheter Cardiovasc Interv. 2021.
Hashimoto G, Cavalcante JL, Mooney MR, Burns MR, Ukaigwe AC and Garcia S. Assessment of aortic bioprosthetic valve fracture by Computed Tomography Angiography. J Cardiovasc Comput Tomogr. 2021;15:e7-e9.
Garcia S, Cubeddu RJ, Hahn RT, Ternacle J, Kapadia SR, Kodali SK, Thourani VH, Jaber WA, Asher CR, Elmariah S, Makkar R, Webb JG, Herrmann HC, Lu M, Devireddy CM, Malaisrie SC, Smith CR, Mack MJ, Sorajja P, Cavalcante JL, Goessl M, Shroff GR, Leon MB and Pibarot P. 5-Year Outcomes Comparing Surgical Versus Transcatheter Aortic Valve Replacement in Patients With Chronic Kidney Disease. JACC Cardiovasc Interv. 2021;14:1995-2005.
Du Y, Gossl M, Garcia S, Enriquez-Sarano M, Cavalcante JL, Bae R, Hashimoto G, Fukui M, Lopes B, Ahmed A, Schmidt C, Stanberry L, Garberich R, Bradley SM, Steffen R and Sorajja P. Natural history observations in moderate aortic stenosis. BMC Cardiovasc Disord. 2021;21:108.
In-hospital and Readmission Permanent Pacemaker Implantation After Transcatheter Aortic Valve Replacement. Megaly, M, Sedhom R, Elbadawi S, Saad M, Cavalcante, J, Sengupta J, Garcia S. Structural Heart Journal. In press.
Fukui M, Sorajja P, Hashimoto G, Lopes BBC, Stanberry LI, Garcia S, Gössl M, Cheng V, Enriquez-Sarano M, Bapat VN, Lesser JR and Cavalcante JL. Right ventricular dysfunction by computed tomography associates with outcomes in severe aortic stenosis patients undergoing transcatheter aortic valve replacement. J Cardiovasc Comput Tomogr. 2021.
Alperi A, Garcia S and Rodés-Cabau J. Transcatheter valve-in-valve implantation in degenerated surgical aortic and mitral bioprosthesis: Current state and future perspectives. Prog Cardiovasc Dis. 2021.
Garcia S, Fukui M, Dworak M, et al. Clinical Impact of Hypoattenuating Leaflet Thickening after Transcatheter Aortic Valve Replacement. Circulation CV Interventions 2022. Circ Cardiovasc Interv. 2022;15:e 011480. DOI:10.1161/CIRCINTERVENTIONS.121.011480
Morcos, R, Megaly M, Saad M, Garcia S, et al. In-Hospital Outcomes of Transesophageal versus Intracardiac Echocardiography Guided Left Atrial Appendage Closure. CCI 2022.
Sedhom R, Megaly M, Saad M, Elbadawi A, Witzke CF, Garcia S, Latib A and Gafoor SA. Transcatheter edge-to-edge repair of the tricuspid valve: The US experience. Catheter Cardiovasc Interv. 2022.
Association of Left Ventricular Remodeling Assessment by Cardiac Magnetic Resonance With Outcomes in Patients With Chronic Aortic Regurgitation. JAMA Cardiology
Miho Fukui, Vinayak Bapat, Santiago Garcia, Marshall Dworak, Go Hashimoto, Hirotomo Sato, Mario Gössl, Maurice Enriquez-Sarano, John Lesser, João Cavalcante, and Paul Sorajja. Deformation of Transcatheter Aortic Valve Prostheses: Implications for Hypo-Attenuating Leaflet Thickening and Clinical Outcomes. Circulation 2022.
Association Between Early Left Ventricular Ejection Fraction Improvement After Transcatheter Aortic Valve Replacement and 5-Year Clinical Outcomes: An Analysis of the PARTNER Trials and Registries. JAMA cardiology
KereiakesD, Garcia, S. Coronary Obstruction After Transcatheter Aortic Valve Replacement: FromRisk Prediction to Prevention. JSCAI