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​​​​Clinical Trials & Publications

For more information about cardiovascular clinical research at The Christ Hospital, visit the Lindner Research Center.​

List of Active Clinical Trials

  1. Hypertensive Disorders of Pregnancy (O. Quesada: PI)
    Funding: National Institutes of Health, Heart Lung, and Blood Institute
    Status: Enrolling
    Description: Determine the extent to which measures of coronary microvascular dysfunction and biochemical stress are related to abnormalities in cardiac structure and function that persist in women with prior preeclampsia.
  2. EMBARK Pilot (O. Quesada: PI)
    Funding: Investigator-initiated
    Status: Enrolling
    Description: A pilot trial to study the effects of open label treatment of empagliflozin, a SGLT2i, on coronary and peripheral microvascular function in a small cohort of patients with non-obstructive coronary artery disease and coronary microvascular dysfunction diagnosed by coronary functional testing.
  3. Women’s Heart Center Long-term Follow-up Registry (O. Quesada: PI)
    Funding: Investigator-initiated
    Status: Enrolling
    Description: The purpose of this registry is to determine the predictors of adverse outcomes in patients seen within the Women’s Heart Center.
  4. CRT Biorepository (O. Quesada: PI)
    Funding: Investigator-initiated
    Status: Enrolling
    Description: The overarching objective of the CRT Biorepository is to collect biological specimens that are linked to clinical data and patient reported outcomes to facilitate future research (basic, translational, clinical, or mechanistic research).
  5. WARRIOR-Women’s Ischemia Trial to Reduce Events in Non-Obstructive Coronary Arteries (O. Quesada: PI)
    Funding: United States of America, Department of Defense
    Status: In Follow-Up
    Description: The purpose of this study is to determine whether aggressive medication treatment to modify risk factors in women with non-obstructive coronary artery disease but with cardiac symptoms (i.e., chest pain) will reduce major adverse cardiovascular events as compared to usual care.
  6. HARP-Heart Attack Research Program (O. Quesada: PI)
    Funding: Sponsor, Sarah Ross Soter Center of The AHA Go Red for Women Research Network at NYU
    Status: Enrolling
    Description: Diagnostic observational study in patients with myocardial infarction with non-obstructive coronary arteries (MINOCA) to determine the prevalence and composition of disrupted plaque and location of myocardial abnormalities.
  7. Discover Ischemia with Non-Obstructive Coronary Arteries (INOCA) (O. Quesada: PI)
    Funding: Sponsor, Yale Cardiovascular Research Group
    Status: Enrolling
    Description: A prospective, multicenter, registry of stable patients with ischemia and no obstructive coronary artery disease (INOCA) evaluated by coronary angiography, intravascular imaging, and physiologic measurements.
  8. Empower CAD (O. Quesada: PI)
    Funding: Industry Sponsor, Shockwave Medical, Inc.
    Status: Enrolling
    Description: The purpose of the study is to generate real-world clinical evidence associated with coronary intravascular lithotripsy in a population of female subjects with calcified coronary artery disease.
  9. COSIRA II (O. Quesada: co-PI)
    Funding: Industry Sponsor, Neovasc
    Status: Enrolling
    Description: To demonstrate the safety and effectiveness of the coronary sinus reducer system for treatment of patients with refractory angina pectoris treated with maximally tolerated guideline-directed medical therapy who demonstrate objective evidence of reversible myocardial ischemia in the distribution of the left coronary artery and who are deemed unsuitable for revascularization.
  10. Endothelial Function EVA2 HM3 (O. Quesada: co-PI)
    Funding: Industry Sponsor, Abiomed, Inc.
    Status: Enrolling
    Description: To demonstrate differences in endothelial function in end-stage heart failure patients receiving continuous flow EVA2 left ventricular assist device (LVAD) as compared to pulsatile flow HM3 LVAD.
  11. Liberate-OLE 003-007 (O. Quesada: co-PI)
    Funding: Industry Sponsor, LIB Therapeutics, LLC.
    Status: In Follow-Up
    Description: To assess the long-term safety, tolerability, and efficacy after 48 and 72 weeks with monthly dosing of LIB003 300 mg administered subcutaneously. LIB003 is an anti-PCSK9 small binding protein consisting of an Adnectin-fused human serum albumin to prevent its rapid renal clearance and enhance its half-life in circulation. Randomization: none. This is an open label extension of Liberate 003-005, 006 or 011.
  12. ​ARIES HM3 (O. Quesada: co-PI)
    Funding: Industry Sponsor, Abbott Cardiovascular Systems, Inc.
    Status: In Follow-Up
    Description: To study the safety and efficacy of an anti-platelet-free antithrombotic regimen in patients with advanced heart failure treated with the Heart Mate 3 (HM3 LVAS). The HM3 is FDA approved. Vitamin K antagonist therapy will be per standard of care with a target INR of 2.0-3.0. Randomization is 1:1 to 100mg aspirin versus placebo.
  13. ELITE (O. Quesada: co-PI)
    Funding: Industry Sponsor, Medtronic
    Status: In Follow-Up
    Description: Post-market clinical follow-up to confirm long-term safety and performance of the InterStim Micro System for sacral neuromodulation. The indications under investigation are overactive bladder, fecal incontinence, and non-obstructive urinary retention. Nonrandomized, open label study.
  14. MICRO-2 (O. Quesada: PI)
    Funding: Industry Sponsor, Genetesis, Inc.
    Status: Enrolling
    Description: A trial to validate CardioFlux MCG’s ability to diagnose myocardial ischemia caused by coronary microvascular dysfunction in patients with suspected INOCA by using diagnostic measures of coronary flow reserve (CFR) via invasive angiography as a reference standard for diagnosis. Prospective, multicenter, observational study.
​

List of Inactive Clinical Trials

  1. MICRO trial (O. Quesada: PI)
    Funding: Genetesis
    Status: Closed
    Description: Multi-center prospective observational study of ANOCA patients to investigate the ability and accuracy of magnetocardiography to detect coronary microvascular dysfunction as compared to reference-standard invasive coronary flow reserve.
  2. Freedom (O. Quesada: co-PI)
    Funding: Industry Sponsor, Caladrius Biosciences
    Status: Closed
    Description: Evaluation of the efficacy and safety of autologous CD34+ cells (CLBS16) in subjects with coronary microvascular dysfunction and without obstructive coronary artery disease.
  3. EMBARK / MyoKardia (O. Quesada: co-PI)
    Funding: Industry Sponsor, MyoKardia, Inc.
    Status: Closed
    Description: Phase 2a proof of concept study to assess safety, tolerability, and preliminary efficacy of mavacamten treatment on cardiac troponin I (cTnI) levels and N-terminal pro-type natriuretic peptide (NT-proBNP) levels in participants with heart failure with preserved ejection fraction (HFpEF) and chronic elevation of cTnl and/or NT-proBNP.
  4. Liberate-H2H 003-011 (O. Quesada: PI)
    Funding: Industry Sponsor, LIB Therapeutics, LLC.
    Status: Closed
    Description: To evaluate the efficacy and safety of LIB003 compared to Evolocumab and Alirocumab in patients with or at high risk for cardiovascular disease, on stable lipid-lowering therapy requiring additional LDL reduction. LIB003 is an anti-PCSK9 small binding protein consisting of an Adnectin-fused human serum albumin in order to prevent its rapid renal clearance and enhance its half-life in circulation. Randomization is 2:2:1 to LIB003 or Repatha or Praluent every 4 weeks.
  5. Liberate-HR 003-006 (O. Quesada: co-PI)
    Funding: Industry Sponsor, LIB Therapeutics, LLC.
    Status: Closed
    Description: To evaluate the long-term efficacy and safety of LIB003 in patients with cardiovascular disease or at high risk for cardiovascular disease on stable lipid-lowering therapy requiring additional LDL reduction. LIB003 is an anti-PCSK9 small binding protein consisting of an Adnectin-fused human serum albumin in order to prevent its rapid renal clearance and enhance its half-life in circulation. Randomization is to LIB003 or placebo (2:1 respectively) every 4 weeks.
  6. Liberate-CVD 003-005 (O. Quesada: co-PI)
    Funding: Industry Sponsor, LIB Therapeutics, LLC.
    Status: Closed
    Description: To evaluate the long-term efficacy and safety of LIB003 in patients with cardiovascular disease on stable lipid-lowering therapy requiring additional LDL reduction. LIB003 is an anti-PCSK9 small binding protein consisting of an Adnectin-fused human serum albumin in order to prevent its rapid renal clearance and enhance its half-life in circulation. Randomization is to LIB003 or placebo (2:1 respectively) every 4 weeks.

Recent Publications by Women’s Heart Center Faculty

  1. Tapp DN, Ashokprabhu N, Hamstra MS, Losekamp M, Schmidt C, Palmer C, Gallatin J, Tierney D, Henry TD, Quesada O. Developing a Women's Heart Center with a Specialization in Coronary Microvascular and Vasomotor Dysfunction (CMVD): If You Build It, They Will Come. 2024. Catheter Cardiovasc Interv. 2024 Nov 6. doi: 10.1002/ccd.31281. Epub ahead of print. PMID: 39506505
  2. Quesada O, Ashokprabhu N, Tapp D, Hamstra MS, Losekamp M, Schmidt C, Palmer C, Gallatin J, Tierney D, Henry TD. Utilizing Invasive Coronary Functional Testing in a Coronary Microvascular and Vasomotor Dysfunction Program: Methods and Considerations. 2024. CCI. In Press.
  3. Fox J, Ali F, Lopez M, Shah SA, Schmidt CW, Quesada O, Henry TD, Verduzco-Gutierrez M. Enhanced External Counterpulsation Improves Dyspnea, Fatigue, and Functional Capacity in Patients with Long COVID. COVID. 2024; 4(9):1379-1385.
  4. Ashokprabhu N, Ziada K, Schmidt CW, Daher E, Cho L, Palmer C, Henry TD, Pepine CJ, Quesada O. Evaluation of Coronary Microvascular Dysfunction Using Magnetocardiography: A New Application to an Old Technology. Am Heart J Plus. 2024 Jul 10;44:100424. PMID: 39108843; PMCID: PMC11301233.
  5. Tzoumas A, Quesada O, Henry TD. Invited Editorial. When is it a Bridge too far? JSCAI. 2024 Aug 12:102244, 10.1016/j.jscai.2024.102244. In Press.
  6. Quesada O, Tapp DN, Ashokprabhu N, Hamstra MS, Palmer C, Gallatin J, Tierney D, Frizzell J, Henry T. Developing a Women's Heart Center with a Specialization in Coronary Microvascular and Vasomotor Dysfunction (CMVD): If You Build It, They Will Come. Accepted CCI.
  7. Ebong IA, Quesada O, Fonkoue IT, Mattina D, Sullivan S, Oliveira GMM, Spikes T, Sharma J, Commodore Y, Ogunniyi MO, Aggarwal NR, Vaccarino V; American College of Cardiology Cardiovascular Disease in Women Committee. The Role of Psychosocial Stress on Cardiovascular Disease in Women: JACC State-of-the-Art Review. J Am Coll Cardiol. 2024 Jul 16;84(3):298-314. doi: 10.1016/j.jacc.2024.05.016. PMID: 38986672; PMCID: PMC11328148.
  8. Benson TW, Pike MM, Spuzzillo AR, Hicks SM, Pham M, Mix DS, Brunner S, Wadding-Lee CA, Conrad KA, Russell HM, Jennings CL, Coughlin TM, Aggarwal A, Lyden SP, Mani K, Bjorck M, Wanhainen A, Bhandari R, Lipworth L, Robinson-Cohen C, Caputo FJ, Shim S, Quesada O, Tourdot B, Edwards TL, Tranter M, Gardiner EE, Mackman N, Cameron SJ, Owens Iii AP. Soluble Glycoprotein VI Predicts Abdominal Aortic Aneurysm Growth Rate and is a Novel Therapeutic Target. Blood. 2024 Jun 20:blood.2023021655. doi: 10.1182/blood.2023021655. Epub ahead of print. PMID: 38900973.
  9. Fox J, Verduzco-Gutierrez M, Sanchez S, Lopez M, Ali F, Quesada O, Henry TD, Shah SA. Enhanced External Counterpulsation Improves Long COVID Associated Symptoms. Am J Cardiol. 2024 Aug 1;224:12-13. doi: 10.1016/j.amjcard.2024.05.037. Epub 2024 Jun 11. PMID: 38866353; PMCID: PMC11257783.
  10. Quesada O, Crousillat D, Rodriguez F, Bravo-Jaimes K, Briller J, Ogunniyi MO, Mattina DJ, Aggarwal NR, Rodriguez CJ, De Oliveira GMM, Velarde G. Cardiovascular Disease in Hispanic Women: JACC Review Topic of the Week. J Am Coll Cardiol. 2024 Apr 30;83(17):1702-1712. doi: 10.1016/j.jacc.2024.02.039. PMID: 38658109.
  11. Quesada O, Wu M, DeFranco E, Bello N, Wong M.S, Parbon, M, Minissian M, Chandra A, Makarem N, Aviles-Santa L, Rodriguez C, Vladutiu CJ, Talavera G, Henry D, Henry T, Bairey Merz CN, Sofer, T, Claggett, B, Solomon S, Cheng S. Cardiac Abnormalities in Hispanic/Latina Women with Prior De Novo Hypertensive Disorders of Pregnancy. Hypertension. 2024 Feb;81(2):255-263. doi: 10.1161/HYPERTENSIONAHA.123.21248. Epub 2023 Dec 4. PMID: 38047358; PMCID: PMC10793810.
  12. Roca Alvarez Y, Pico M, Ashokprabhu N, Abou-Amro K, Bailey S, Pung E, Oberholster E, Quesasda O. Polycystic Ovarian Syndrome a Risk Factor for Cardiovascular Disease. Curr Atheroscler Rep. 2023 Dec;25(12):1003-1011. doi: 10.1007/s11883-023-01168-1. Epub 2023 Dec 4. PMID: 38048007.
  13. Ashokprabhu N, Fox J, Henry TD, Schmidt CW, Tierney D, Gallatin J, Roca Alvarez Y, Thompson L, Hamstra M, Shah S, Quesada O. ANOCA, angina and no obstructive coronary artery disease, Enhanced External Counter Pulsation, EECP, Coronary Microvascular Dysfunction. Am J Cardiol. 2024 Jan 15;211:89-93. doi: 10.1016/j.amjcard.2023.10.061. Epub 2023 Oct 27. PMID: 37890564.
  14. Ashokprabhu ND, Fox J, Shah SA, Roca Alvarez Y, Schmidt CW, Tierney D, Thompson L, Henry TD, Quesada O. Enhanced External Counterpulsation for the Treatment of Angina with Nonobstructive Coronary Artery Disease (ANOCA). Am J Cardiol. 2023 Oct 27:S0002-9149(23)01213-4. PMID: 37890564; PMCID: PMC11188706.
  15. Quesada O, Yildiz M, Henry TD, Bergstedt S, Chambers J, Shah A, Stanberry L, Volpenhein L, Aziz D, Lantz R, Palmer C, Ugwu L, Ahsan MJ, Garberich RF, Rohm HS, Aguirre FV, Garcia S, Sharkey SW. Mortality in STEMI with Non-Obstructive Coronary Arteries (MINOCA) and Mimickers. JAMA Network Open. 2023 Nov 1 ;6(11):e2343402. doi: 10.1001/jamanetworkopen.2023.43402. PMID: 36798420 PMCID: PMC9934717
  16. Samuels BA, Shah SM, Widmer RJ, Kobayashi Y, Miner SES, Taqueti VR, Jeremias A, Albadri A, Blair JA, Kearney KE, Wei J, Park K, Barseghian El-Farra A, Holoshitz N, Janaszek KB, Kesarwani M, Lerman A, Prasad M, Quesada O, Reynolds HR, Savage MP, Smilowitz NR, Sutton NR, Sweeny JM, Toleva O, Henry TD, Moses JW, Fearon WF, Tremmel JA; Microvascular Network (MVN). Comprehensive Management of ANOCA, Part 1-Definition, Patient Population, and Diagnosis: JACC State-of-the-Art Review. J Am Coll Cardiol. 2023 Sep 19;82(12):1245-1263. doi: 10.1016/j.jacc.2023.06.043. PMID: 37704315.
  17. Smilowitz NR, Prasad M, Widmer RJ, Toleva O, Quesada O, Sutton NR, Lerman A, Reynolds HR, Kesarwani M, Savage MP, Sweeny JM, Janaszek KB, Barseghian El-Farra A, Holoshitz N, Park K, Albadri A, Blair JA, Jeremias A, Kearney KE, Kobayashi Y, Miner SES, Samuels BA, Shah SM, Taqueti VR, Wei J, Fearon WF, Moses JW, Henry TD, Tremmel JA; Microvascular Network (MVN). Comprehensive Management of ANOCA, Part 2-Program Development, Treatment, and Research Initiatives: JACC State-of-the-Art Review. J Am Coll Cardiol. 2023 Sep 19;82(12):1264-1279. doi: 10.1016/j.jacc.2023.06.044. PMID: 37704316.
  18. Aziz D, Yildiz M, Quesada O, Henry TD.  COVID-19 STEMI Related to Microthrombi May Lead to Coronary Microvascular Dysfunction. Catheter Cardiovasc Interv. 2023 Oct;102(4):641-645. Epub 2023 Aug 25. PMID: 37622612.
  19. Suppogu N, Tjoe B, Wei J, Maughan J, Joung S, Quesada O, Shufelt C, Samuels B, Azarbal B, Bairey Merz CN. Case Report: Repeat Coronary Function Testing in Women with Ischemia and No Obstructive Coronary Artery Disease. Front Cardiovasc Med. 2023 Jul 6;10:1096265. PMID: 37485267 PMCID: PMC10357037
  20. Ashokprabhu ND, Quesada O, Alvarez YR, Henry TD. INOCA/MINOCA: Mechanisms and Novel Treatments. Am Heart J Plus. 2023 June;30:100302. PMID: 37377840 PMCID: PMC10299803
  21. Quesada O, Wei J, Suppogu N, Cook-Wiens G, Lauzon M, Reis S, Shaw L, Sopko G, Handberg E, Pepine C, C Bairey Merz N. Fitness attenuates long-term cardiovascular outcomes in women with ischemic heart disease and metabolic syndrome. Am J Prev Cardiol. 2023 April 23;14:100498. PMID: 37181803 PMCID: PMC10172715
  22. Ashokprabhu N, Roca Y, Quesada O. Invited Editorial: Female Sex and Acute Heart Failure Predict Mortality Following Acute Coronary Syndrome. JACC Adv. 2023 May 26;2(3):100353. PMID: 38939606; PMCID: PMC11198233.
  23. Mehta PK, Levit RD, Wood MJ, Aggarwal N, O'Donoghue ML, Lim SS, Lindley K, Gaignard S, Quesada O, Vasta N, Leon A, Volgman AS, Malas W, PepineCJ, on behalf of the American College of Cardiology Cardiovascular Disease in Women Committee. Chronic Rheumatologic Diseases and Cardiovascular Disease Risk in Women. Am Heart J Plus: Cardiology Research and Practice. March 2023;27(100267). PMID: 38511090; PMCID: PMC10945906.
  24. Shah SM, Quesada O, Henry TD.  The Challenge of Myocardial Bridging. J Soc Cardiovasc Angiogr Interv. 2023 January 3;1(100545).
  25. Quesada O, Scantlebury D, Briller J, Michos ED, Aggarwal NR. Markers of Cardiovascular Risk Associated with Pregnancy. Curr Cardiol Rep. 2023 Feb;25(2):77-87. PMID: 36745273 PMCID: PMC10278153
  26. Yildiz M, Ashokprabhu N, Shewale A, Pico M, Henry TD, Quesada O. Invited Review: Myocardial Infarction with Non -Obstructive Coronary Arteries (MINOCA). Front Cardiovasc Med. 2022 November 15;9:1032436. PMID: 36457805 PMCID: PMC9705379
  27. Torosyan N, Aziz D, Quesada O. Long term sequelae of adverse pregnancy outcomes. Maturitas. 2022 Nov;165:1-7. PMID: 35816901
  28. Ogunniyi MO, Hayes SE, Mahmoud Z, Commodore-Mensah Y, Fleg JL, Fatade Y, Quesada O, Aggarwal N, Mattina D, Oliveria GM, Lindley K, Ovbiagele B, Roswell RO, Douglass P, Itchhaporia D. Eliminating Disparities in Cardiovascular Disease for Black Women: From "Admiring the Problem" to Action. JACC Review Topic of the Week. 2022 Nov 1;80(18):1762-1771. PMID: 36302590 PMCID: PMC10278154
  29. Quesada O, Henry TD. Invited Article: Coronary Microvascular Disease in Patients with Obstructive Coronary Artery Disease. Cardiology. 2022 October 28. American College of Cardiology Magazine Spotlight Series. https://www.acc.org/Latest-in-Cardiology/Articles/2022/10/01/01/42/Spotlight-Series-Microvascular-Dysfunction-C​oronary-Microvascular-Disease-in-Patients-With-Obstructive-CAD
  30. Henry TD, Quesada O, Wilson RF. Invited Editorial: Time Course of “Microvascular" Stunning in STEMI. Circ Cardiovasc Interv. 2022 Oct 28;15:e12528. PMID: 36305317 PMCID: PMC9988249 
  31. Zahid S, Harrington C, Michos E, Baker V, Quesada O, Shufelt C, Aggarwal N, Hashem A, Minhas A. Cardiovascular Complications During Delivery Admissions Associated with Assisted Reproductive Technology (From a National Inpatient Sample Analysis 2008-2019). Am J Cardiol. 2022 Oct 22;S0002-9149(22):00953-5. PMID: 36283885
  32. Minissian M, Mehta P, Hayes S, Park K, Wei J, C Bairey Merz N, Cho L, Volgman A, Elgendy I, Mamas M, Davis M, Reynolds H, Epps K, Lindley K, Wood M, Quesada O, Piazza G, Pepine C. Ischemic Heart Disease in Young Women: JACC Review Topic of the Week. J Am Coll Cardiol. 2022 Sep;80(10):1014-1022. PMID: 36049799 PMCID: PMC9847245
  33. Makarem M, Alcantara C, Musick S, Quesada O, Sears DD, Chen Z, Tehranifar P.  Multidimensional Sleep Health is Associated with Cardiovascular Disease Prevalence and Cardiometabolic Health in a Nationally Representative Sample of US Adults. Int J Environ Res Public Health. 2022 Aug 29;19:10749. PMID: 36078471 PMCID: PMC9518578
  34. Sarma AA, Aggarwal NR, Briller JE, Davis M, Economy KE, Elkayam U, Hameed A, Januzzi JL, Lindley KJ, Mattina DJ, McBay B, Quesada O, Scott NS on behalf of the American College of Cardiology Cardiovascular Disease in Women Committee and Cardio Obstetrics Committee. The Utilization and Interpretation of Cardiac Biomarkers During Pregnancy. JACC Adv. 2022 August;1(3):1-13.
  35. Briller JE, Aggarwal NR, Davis MB, Hameed AB, Malhame I, Mahmoud Z, McDonald EG, Moraes de Oliveira G, Quesada O, Scott NS, Sharma J on behalf of the American College of Cardiology Cardiovascular Disease in Women Committee. Cardiovascular Complications of Pregnancy-Associated COVID-19 Infections. JACC Adv. 2022 August;1(3):1-11. PMID: 35967591 PMCID: PMC9364954
  36. Lantz R, Quesada O, Mattingly G, Henry TD. Contemporary Management of Refractory Angina. Interv Cardiol Clin. 2022 Jul;11(3):279-292. PMID: 35710283 PMCID: PMC9275781
  37. Quesada O, Van Hon L, Yildiz M, Madan M, Sanina C, Davidson L, Htun WW, Saw J, Garcia S, Deghani P, Stanberry L, Bortnick A, Henry TD, Grines C, Benziger C. Invited Manuscript. Sex Differences in Clinical Characteristics, Management Strategies, and Outcomes of STEMI with COVID-19: NACMI Registry. J Soc Cardiovasc Angiogr Interv. 2022 Jul-Aug;1(4):100360. PMID: 35812987 PMCID: PMC9117757  
  38. Sharma J, McAlister J, Aggarwal NR, Wei J, Mehta PK, Quesada O, Mattina D, Scott NS, Mahmoud Z, Kurrelmeyer K, Moraes De Oliveira GM, Lindley KJ. Evaluation and Management of Blood Lipids Through a Woman's Life Cycle. Am J Prev Cardiol. 2022 March 13;10:100333. PMID: 35345879 PMCID: PMC8956895
  39. Quesada O, Wei J, Lauzon M, Suppogu N, Buttle R, Kelsey S, Reis S, Shaw L, Sopko G, Handberg E, Pepine C, C Bairey Merz N. Body weight and physical fitness in women with ischemic heart disease: Does physical fitness contribute to our understanding of the obesity paradox in women? Eur J Prev Cardiol. 2022 Mar 4;zwac046. PMID: 35244151 PMCID: PMC9440958
  40. Quesada O, Elboudwarej O, Nelson M, Al-Badri A, Mastali M, Wei J, Zarrabi B, Suppogu N, Aldiwani H, Mehta P, Shufelt C, Cook-Wiens G, Berman D, Thomson L,  Handberg E,  Pepine C, Van Eyk J, C Bairey Merz N. Ultra-high Sensitivity Cardiac Troponin-I Concentration and Left Ventricular Structure and Function in Women with Ischemia and No Obstructive Coronary Artery Disease. Am Heart J Plus: Cardiology Research and Practice. 2022 March 3;13:100115. PMID: 35784010 PMCID: PMC9246284
  41. Aldiwani H, Nelson DM, Sharif B, Wei J, Samuel T. J, Suppogu N, Quesada O, Cook-Wiens G, Gill E, Szczepaniak S. L, Thomson EJT, Tamarappoo B, Asif A, Shufelt C, Berman D, Bairey Merz CN. Reduced Myocardial Perfusion Is Common Among Subjects with Ischemia and No Obstructive Coronary Artery Disease and Heart Failure with Preserved Ejection Fraction: A Report from the WISE-CVD Continuation Study. Vessel Plus. 2022;6:16. Epub 2022 March 5. PMID: 35836794 PMCID: PMC9278056
  42. O'Kelly CA, Michos ED, Shufelt CL, Vermunt JV, Minissian MB., Quesada O., Smith G, Rich-Edwards JW, Garovic VD, El Khoudary SR, Honigberg MC. Pregnancy and Reproductive Risk Factors for Cardiovascular Disease in Women. Circ Res. 2022 Feb 18;130(4):652–672. PMID: 35175837. PMCID: PMC8870397
  43. Henry Y, C Bairey Merz N, Wei J, Corban M, Quesada O, Joung S, Kotynski C, Wang J, Lewis M, Schumacher A, Bartel R, Takagi H, Shah V, Sietsema W, Losordo D, Lerman A. Autologous CD34+ stem cell therapy increases coronary flow reserve and reduces angina in patients with coronary microvascular dysfunction. Circ Cardiovasc Interv. 2022 Feb;15(2):e010802. PMID: 35067072 PMCID: PMC8843403
  44. Mehta P, Quesada O, Al-Badri A, Fleg J, Volgman AS, Pepine C, Bairey Merz CN, Shaw LJ. Ischemia and No Obstructive Coronary Arteries in Patients with Stable Ischemic Heart Disease. Int J Cardiol. 2021 Dec 11;S0167-5273(21)02005-2. doi: 10.1016/j.ijcard.2021.12.013. PMID: 34902504  PMCID: PMC8779638
  45. Mehta PK, Wei J, Shufelt C, Quesada O, Shaw L, Bairey Merz CN. Gender-Related Differences in Chest Pain Syndromes in the Frontiers in CV Medicine Special Issue: Sex and Gender in CV Medicine. Front Cardiovasc Med. 2021 November 17;8:744788. PMID: 34869650 PMCID: PMC8635525
  46. Lindley JK, Aggarwal RN, Briller EJ, Davis BM, Douglass P, Epps CK, Fleg LJ, Hayes S, Itchhaporia D, Mahmoud Z, Moraes De Oliveira G, Ogunniyi OM, Quesada O, Russo MA, Sharma J, Wood JM. Socioeconomic Determinants of Health and their Relationship to Cardiovascular Outcomes in Women: JACC Review Topic of the Week. J Am Coll Cardiol. 2021 Nov 9;78(19):1919-1929. PMID: 34736568
  47. Quesada O, Henry TD. Functional coronary angiography for coronary microvascular function: the time has come! Catheter Cardiovasc Interv. 2021 Nov 1;98(5):836-837. doi: 10.1002/ccd.29971. PMID: 34752008 PMCID: PMC9246295
  48. Quesada O, Claggett B, Rodriguez F, Cai J, Moncrieft AE, Garcia K, Del Rios Rivera M, Hanna DB, Daviglus ML, Talavera GA, Bairey Merz CN, Solomon SD, Cheng S, Bello NA. Associations of Insulin Resistance with Systolic and Diastolic Blood Pressure: A Study From the HCHS/SOL. Hypertension. 2021 Sep;78(3):716-725. PMID: 34379440 PMCID: PMC8650976
  49. Mehta PK, Thomson LEJ, Slomka PJ, Hayes SW, Friedman JD, Swift A, Quesada O, Wei J, Shaw LJ, Nelson MD, Li L, Hermel D, Hermel MH, Irwin MR, Krantz DS, Travin MI, Pepine CJ, Berman DS, Bairey Merz CN. Cardiac Sympathetic Activity by I-Meta-Iodobenzylguanidine Imaging in Women With Coronary Microvascular Dysfunction: A Pilot Study. JACC Cardiovasc Imaging. 2021 Sep;14(9):1873-1875. PMID: 34147436  PMCID: PMC9186182
  50. Rai B, Shukla J, Henry TD, Quesada O. Angiogenic CD34 Stem Cell Therapy in Coronary Microvascular Repair-A Systematic Review. Cells. 2021 May 8;10(5):1137. doi: 10.3390/cells10051137. PMID: 34066713 PMCID: PMC8151216
  51. Quesada O, Shandhi MMH, Beach S, Dowling S, Tandon D, Heller J, Etemadi M, Roy S, Gonzalez Velez JM. Use of Ballistocardiography to Monitor Cardiovascular Hemodynamics in Preeclampsia. Womens Health Rep (New Rochelle). 2021 Apr 20;2(1):97-105. PMID: 33937907 PMCID: PMC8080913
  52. Bello NA, Bairey Merz CN, Brown H, Davis MB, Dickert NW, El Hajj SC, Giullian C, Quesada O, Park K, Sanghani RM, Shaw L, Volgman AS, Wenger NK, Williams D, Pepine DJ, Lindley KJ; American College of Cardiology Cardiovascular Disease in Women Committee and the Cardio-Obstetrics Work Group. Diagnostic Cardiovascular Imaging and Therapeutic Strategies in Pregnancy: JACC Focus Seminar 4/5. J Am Coll Cardiol. 2021 Apr 13;77(14):1813-1822. PMID: 33832607 PMCID: PMC8221542
  53. Quesada O, Henry TD. New Generation Drug Eluting Stents: Closing the Gap in Sex Disparity in Cardiovascular Outcomes in Women. Catheter Cardiovasc Interv. 2021 Apr 1;97(5):805-806. PMID: 33851789 PMCID: PMC8252807
  54. Suppogu N, Wei J, Quesada O, Shufelt C, Cook-Wiens G, Samuels B, Petersen JW, Anderson D, Handberg EM, Pepine CJ, Bairey Merz CN. Angina Relates to Coronary Flow in Women with Ischemia and No Obstructive Coronary Artery Disease. Int J Cardiol. 2021 Mar 1;S0167-5273(21)00373-9. PMID: 33662486 PMCID: PMC8107128
  55. Volgman AS, Benjamin EJ, Curtis AB, Fang MC, Lindley KJ, Naccarelli GV, Pepine CJ, Quesada O, Vaseghi M, Waldo AL, Wenger NK, Russo AM; American College of Cardiology Committee on Cardiovascular Disease in Women. Women and Atrial Fibrillation. J Cardiovasc Electrophysiol. 2020 Dec 17. PMID: 33332669 PMCID: PMC8281363 
  56. AlBadri A, Wei J, Quesada O, Mehta PK, Xiao Y, Ko Y, Anderson RD, Petersen J, Azarbal B, Samuels B, Henry TD, Cook-Wiens G, Handberg EM, Van Eyk J, Pepine CJ, Bairey Merz CN. Coronary Vascular Function and Cardiomyocyte Injury: A Report WISE-CVD. Arterioscler Thromb Vasc Biol. 2020. Dec;40(12):3015-3021. PMID: 33028098 PMCID: PMC8079158
  57. ​Quesada O, Henry TD. STEMI in young women: Don't miss spontaneous coronary artery dissection! Catheter Cardiovasc Interv. 2020 Nov;96(6):1231.1232. PMID: 33217189 PMCID: PMC8284602


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